Why is it so difficult to find a 200ul Conductive Filter Tips? The first thing to consider is the accuracy and precision of the pipette tips. The shapes of the tips vary due to differences in build quality control. Although the price difference is small, it still adds up to a lot of variability. To reduce variability, you can buy high quality tips.
BRAND Pipette Tips
BRAND pipette tips are difficult to find for several reasons. First of all, they are designed for specific pipettes. When the tips are not matched, air and moisture can escape from the pipette barrel, causing the volume of liquid to be incorrectly aspirated. Additionally, if you are using a non-brand pipette, the tips are not a good fit, resulting in inaccuracy.
Another reason why BRAND pipette tips are so hard to find is the lack of quality. Some manufacturers, such as Tecan, have made it difficult to buy pipette tips for their machines, and they are forced to use up their emergency supply for a while. This means that the company has had to cut back on its production, which can cause a shortage. However, the shortage has caused some companies to look for cheaper alternatives.
Lack of Quality Pipette Tips
Aside from the lack of quality pipette tips, the availability of cheap and low-retention pipette tips has also been an issue for labs. The COVID pandemic has made it difficult to find the high-quality pipette tips that are widely used. Without a doubt, the quality of these tips is crucial to the success of your assay.
In addition to the shortage of cheap pipette tips, the shortage has caused a disruption in the supply chain. Pipette tips are essential for Covid-19 and other lab tests. However, pipette tips can also be disrupted by natural disasters or freak accidents. The recent statewide blackout in Texas killed more than 100 people and forced companies to shut down their manufacturing facilities.
Variety of Different Micropipettes
Universal pipette tips are designed to fit a variety of different micropipettes on the market. The tip should not require force to fit a particular pipette. Some manufacturers design universal tips with flexible ends that fit different pipettes. In addition, universal pipette tips have many features, including hydrophobic, graduated, filtered, and sterile. Some of the features of universal tips are listed below:
The first important characteristic to look for in a pipette tip is the polypropylene blend. Ideally, the tip is made of virgin polypropylene without any plastic or metal additives. This means that it is safe to use in experiments. You also want to look for colored tips without metal additives, which are often used to make dyes. This is important if you’re using pipette tips for sensitive samples.
Since pipette tips are so scarce in many laboratories, they’ve had to be swapped between researchers. The shortage has forced many biotech companies to prioritize their experiments. If it continues to get worse, scientists may have to abandon portions of their work. If it persists, however, the shortage will be worse than ever. Therefore, it’s crucial for researchers to plan ahead and find alternate ways to obtain pipette tips.
Prevent Contamination During PCR Experiments
Pipette tips are used to prevent contamination during PCR experiments. During aspiration, filter tips prevent contaminated aerosols from entering the pipette cone and contaminating the PCR sample. However, certain sample agents may bind to filter material, making them unavailable for DNA amplification. To avoid this problem, pipette tips with high recovery rates are recommended.
Filter tips used for RT-PCR must be free from PCR inhibitors. For this reason, the tips should be sterilized and produced in a clean room without human contact. Most filter tips are labeled as RNase/DNase and human pyrogen free. The pyrogen-free ones are often made from non-recycled materials. However, the PCR inhibitors may still be present in some tips.
The CDC’s requirements for detecting SARS-CoV-2 and COVID-19 also created a demand for filter tip pipette tips. But the global demand for filter tips far outpaced supply. Unfortunately, the shortage may last until 2021. Regardless of the causes, the problem isn’t over yet. In the meantime, pipette tips with barrier coatings are a valuable resource for diagnostic molecular biology and biomedical research.
Last Words:
Good pipette tips are made from virgin polypropylene resin. Some include metals and chemicals used in injection molds, as well as plastic additives. Ensure your filtered tips are free of cellulose, RNase, DNA, Pyrogen, and PCR inhibitors. There are several types of pipette tips, including the specialized ones. To avoid any PCR inhibitors, look for the certified tip.
