Interferon-gamma or IFN Ī³ or is a human dimerized soluble protein encoded by the IFNG gene. The biologically active IFN Ī³ is an interlocking anti-parallel form of two monomers. IFN Ī³ is the sole member of the type II IFN group. Interferon-gamma (IFN-Ī³) is a protein coded for by the IFNG gene. The biologically active IFN-gamma is an interlocking anti-parallel form of two monomers. You may also hear IFN-Ī³ referred to as immune interferon or simply interferon gamma, but no matter what you call it, this cytokine is a crucial part of your immune system.
Interferon gamma protein is a soluble protein involvedĀ in the innate immune response. It is a subunit of type II interferon ribonucleoproteins (IRNPs) and it is encoded by the IFNG gene. This gene encodes the sole member of the type II interferon family of proteins, which are products of immune response genes. Interferon gamma binds to interferon gamma receptor (IFNGR) complex to elicit a cellular signal. This cytokine plays a crucial role in innate and adaptive immunity.
The biological active IFN Ī³ is an interlocking anti-parallel form of two monomers. This protein binds to the IFN-Ī³ receptor complex to elicit a cellular signal. Two subunits, IFNGR1 and IFNGR2, make up the IFN-Ī³ receptor complex. This protein plays a crucial role in innate and adaptive immunity. It inhibits viral replication, fights against bacteria, and modulates and stimulates the immune system. When you look up āWhat is Interferon Gamma?ā you may come across its former name, immune interferon.
Cystatin C antibody is a basic non-glycosylated protein characterized by long and short alpha-helices. Although researchers mainly use cystatin C levels and study the cystatin C glomerular filtration rate (GFR) to detect kidney disorders, recent studies also explore cystatin Cās role in predicting cardiovascular diseases and association with amyloid plaques in neurological disorders. The cystatin C test is used to diagnose kidney disease and to determine the glomerular filtration rate. The development of new technologies have enabled researchers to develop an assay for cystatin C (CST3). New applications of this test are to evaluate cardiovascular diseases and amyloid plaques in neurological disorders.
Cystatin C is a biomarker mainly used to detect kidney disorders. Cystatin C is a member of the family of type 2 cystatins. There are three kinds of type 2 cystatins: cystatin C, cystatin N, and cystatin S. What exactly are type 2 cystatins? They are present in all nucleated human cells, and they inhibit serine proteases that degrade extracellular matrix proteins.
Cystatin C is an important kidney biomarker. Researchers first described Cystatin C as a gamma trace found in the urine and cerebrospinal fluid of patients with kidney failure. All nucleated human cells produce cystatin C, which is also named neuroendocrine-basic polypeptide or post-gamma-globulin. The antigens encoded by CST3 gene fall into three major categories: type 1 and 2 cystatins, hepcidin anti-trypsin inhibitor, and coiled-coil proteins. The human CST3 gene is located in 9q34 on chromosome 9. When you search for āwhat is cystatin c testā, you will come across other aliases for Cystatin C are cystatin 3, formerly known as post-gamma-globulin, neuroendocrine-basic polypeptide, and gamma trace.
