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Know More About Tumor Necrosis Factor Alpha Test

The TNFα test measures tumour necrosis factor-alpha (TNF-α) from 1 to 400 pg/ml with a sensitivity of 1 pg/ml, and a minimum sample volume of 0.1 ml. This test is for research use only and is not intended for diagnostic use. The level of tumour necrosis factor alpha may be elevated in diseases such as autoimmune diseases, some viral infections, septic shock, macrophage activation syndrome, chronic inflammation and leukemia. Tumor Necrosis Factor (TNF), or often referred to as TNFα, is a polypeptide (protein) of about 17 kDa that acts as a cytokine. It is an enzyme-inducing protein and an inflammatory regulator. As it is a member of the TNF superfamily, it bears many similarities to other proteins in the superfamily, such as lymphotoxin (LT), lymphotoxin alpha (LT-α), LT-beta (LTβ), tumour necrosis factor beta (TNFβ), CD30 ligand, CD30L, 4-1BB Ligand and CD40 ligand.

The tumor necrosis factor alpha test (TNF-1) is a blood test that measures the amount of TNF-α in your blood. TNF-α, or tumor necrosis factor-alpha, is a protein found naturally in the body and a part of the human immune system. Released by macrophages, TNF-α triggers a response against infections and foreign substances in the body. A TNF-α test may show elevated levels in people who have an inflammatory disease such as arthritis, colitis, Crohn’s disease, liver or kidney diseases, or immune disorders like systemic lupus erythematosus (SLE), scleroderma and rheumatoid arthritis.

What is granulate colony stimulation factor or g csf? G csf structure (G-CSF or GSCF) or Colony Stimulating Factor 3 (CSF 3), is a glycoprotein with distinct roles in the physiological and pathological condition. It stimulates the bone marrow to produce granulocytes, and stem cells to release them into the bloodstream. G-CSF production typically indicates an endogenous presence of infection or tissue damage, stimulating the generation of G-CSF protein. Several cells can produce G-CSF, but the cognate receptor binding biomarker is principally induced by immune cells such as macrophages and endothelium. A list of synonyms for G-CSF include C17orf33 and CSF3OS.

G-CSF or GSCF is a glycoprotein with distinct roles in the physiological and pathological condition. It stimulates the bone marrow to produce granulocytes and stem cells to release them into the bloodstream. Its name stands for Granulocyte Colony Stimulating Factor due to its role in increasing the production of neutrophils, which are needed to fight infection. G-CSF production indicates an endogenous presence of infection or tissue damage, stimulating the generation of G-CSF protein by multiple cells. G-CSF is chiefly induced by immune or endothelial cells; when searched for, ‘what is G-CSF’, one will likely be directed to relevant information regarding cancer and its treatment or mentions of this protein. 

Granulate Colony Stimulation Factor (G-CSF) or Colony Stimulating Factor 3 (CSF 3) is a glycoprotein involved in the physiology and pathology of an organism, primarily in the generation of granulocytes. G-CSF protein was originally discovered by Gonzalo Campos and Kevin Allison athet University of Melbourne in 1974, although earlier work characterizing agglutinins has been carried out by others. In humans, G-CSF is encoded on chromosome 17 by the CSF3 gene.

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